Topical steroids for ocular disease

Ocular-hypertensive response to topical steroids in children.

OBJECTIVE The purpose of the study is to investigate the rate and degree of ocular-hypertensive response to topical steroids in Chinese children. DESIGN The study design was an institutional, randomized, clinical trial. PARTICIPANTS A total of 19 consecutive patients were studied. INTERVENTION Topical steroids were administered to Chinese children younger than 10 years of age who underwen...

Polysaccharides as Excipients for Ocular Topical Formulations

Topical Use of Steroids in the Aged*

Steroid preparations for topical use include a variety of forms, among them hydrophobic ointments, emulsions, liquids, and gels. These drugs are chosen according to the status and site of the lesion and the patient’s age. There are five grades of steroid preparations for topical use in terms of the potency of their clinical effect. The skin of elderly persons tends to be dry and therefore does ...

topical mitomycin c for partially excised ocular surface squamous neoplasia

purpose : to develop a guideline for the treatment of incompletely removed histopathologically documented ocular surface neoplasia (ossn) with mitomycin c (mmc). materials & methods : through an interventional case series, 17 eyes of 17 patients presented with incompletely removed ossn were treated according to a protocol using 2-3 alternate 7-day courses of mmc 0.04%. clinical recurrence was r...

Pharmacokinet.es of Topical Ocular Phenylephrine HCI

The rates of corneal penetration and efflux of phenylephrine (PE) and its metabolites were found to be limited by the epithelium. The rate constant for corneal penetration as measured in a lucite block perfusion system was 1.06 X 10~ hr" when the epithelium was present and 1.25 X 1O~ hr" when the epithelium was denuded. Epithelial removal reduced the half-time (t)/2) for corneal efflux of PE fr...